Cruises Departing from San Diego
Overview
Do some California dreaming when you search for cruises out of San Diego. The Port of San Diego is located right in the heart of the city, a California gem filled with places to go. There’s great fresh seafood and Mexican cuisine, lovely parks, two major art museums to explore, and if you consider yourself an animal lover and haven’t been to San Diego before, you owe it to yourself to set some time aside for the world-famous zoo and wildlife refuge. Hop on a ship to Mexico, Hawaii or any number of places on the west coast, and be sure to use Dunhill Travel Deals to find the best way to get there.
Itineraries, Sailing Dates & Pricing
15 - Days
Panama Canal
Inside
$1,299
Outside
$2,099
Balcony
$2,199
Suite
$4,999
| Day | Location | Arrive | Depart |
|---|---|---|---|
| 0 | San Diego - California | - | 17:00 |
| 1 | At Sea | - | - |
| 2 | Cabo San Lucas - Mexico | 12:00 | 18:00 |
| 3 | Puerto Vallarta - Mexico | 12:00 | 19:00 |
| 4 | At Sea | - | - |
| 5 | At Sea | - | - |
| 6 | Puerto Quetzal - Guatemala | 06:30 | 18:00 |
| 7 | At Sea | - | - |
| 8 | Puntarenas - Costa Rica | 08:00 | 18:30 |
| 9 | At Sea | - | - |
| 10 | Panama Canal (Cruising) | 06:00 | 18:00 |
| 11 | Colon - Panama | 06:00 | 16:00 |
| 12 | Cartagena - Colombia | 09:00 | 16:00 |
| 13 | At Sea | - | - |
| 14 | At Sea | - | - |
| 15 | Fort Lauderdale - Florida | 07:00 | - |
5 - Days
Mexican Riviera
On Disney Wonder
Inside
$1,134
Outside
$1,179
Balcony
$1,444
Suite
$2,649
| Day | Location | Arrive | Depart |
|---|---|---|---|
| 0 | San Diego | - | 16:00 |
| 1 | Fun Day at Sea | - | - |
| 2 | Cabo San Lucas | 08:30 | 16:45 |
| 3 | Fun Day at Sea | - | - |
| 4 | Ensenada | 08:30 | 16:45 |
| 5 | San Diego | 08:30 | - |
4 - Days
Mexican Riviera
On Disney Wonder
Inside
$1,092
Outside
$1,160
Balcony
$1,376
Suite
$2,140
| Day | Location | Arrive | Depart |
|---|---|---|---|
| 0 | San Diego | - | 16:00 |
| 1 | Fun Day at Sea | - | - |
| 2 | Cabo San Lucas | 08:30 | 15:30 |
| 3 | Fun Day at Sea | - | - |
| 4 | San Diego | 08:30 | - |
5 - Days
Mexican Riviera
On Disney Wonder
Inside
$1,075
Outside
$1,135
Balcony
$1,425
Suite
$2,500
| Day | Location | Arrive | Depart |
|---|---|---|---|
| 0 | San Diego | - | 16:00 |
| 1 | Fun Day at Sea | - | - |
| 2 | Cabo San Lucas | 08:30 | 16:45 |
| 3 | Fun Day at Sea | - | - |
| 4 | Ensenada | 08:30 | 16:45 |
| 5 | San Diego | 08:30 | - |
2 - Days
Mexican Riviera
On Disney Wonder
Inside
$671
Outside
$725
Balcony
$833
Suite
$1,949
| Day | Location | Arrive | Depart |
|---|---|---|---|
| 0 | San Diego | - | 16:00 |
| 1 | Ensenada | 08:15 | 16:45 |
| 2 | San Diego | 08:30 | - |
| Day | Location | Arrive | Depart |
|---|
5 - Days
Mexican Riviera
On Disney Wonder
Inside
$1,020
Outside
$1,130
Balcony
$1,390
Suite
$2,575
| Day | Location | Arrive | Depart |
|---|---|---|---|
| 0 | San Diego | - | 16:00 |
| 1 | Fun Day at Sea | - | - |
| 2 | Cabo San Lucas | 08:30 | 16:45 |
| 3 | Fun Day at Sea | - | - |
| 4 | Ensenada | 08:30 | 16:45 |
| 5 | San Diego | 08:30 | - |
| Day | Location | Arrive | Depart |
|---|
18 - Days
Panama Canal
On Nieuw Amsterdam
Inside
$1,799
Outside
$1,999
Balcony
$2,799
Suite
$4,949
| Day | Location | Arrive | Depart |
|---|---|---|---|
| 0 | San Diego, California, Us | - | 17:00 |
| 1 | At Sea | - | - |
| 2 | At Sea | - | - |
| 3 | Puerto Vallarta, Mexico | 08:00 | 21:00 |
| 4 | Manzanillo, Mexico | 08:00 | 17:00 |
| 5 | At Sea | - | - |
| 6 | Huatulco, Mexico | 08:00 | 17:00 |
| 7 | Puerto Chiapas, Mexico | 08:00 | 17:00 |
| 8 | Puerto Quetzal, Guatemala | 08:00 | 18:00 |
| 9 | Corinto, Nicaragua | 08:00 | 16:00 |
| 10 | Puerto Caldera (Puntarenas), Costa | 08:00 | 18:00 |
| 11 | At Sea | - | - |
| 12 | Enter Panama Canal Balboa | 05:00 | 05:00 |
| 13 | Cruising Panama Canal | - | - |
| 14 | Exit Panama Canal Cristobal | 19:00 | 19:00 |
| 15 | At Sea | - | - |
| 16 | Oranjestad, Aruba | 08:00 | 17:00 |
| 17 | At Sea | - | - |
| 18 | At Sea | - | - |
| 19 | Half Moon Cay, Bahamas | 07:00 | 15:00 |
| 20 | Fort Lauderdale, Florida, Us | 07:00 | - |
2 - Days
Mexican Riviera
On Disney Wonder
Inside
$687
Outside
$713
Balcony
$835
Suite
$1,377
| Day | Location | Arrive | Depart |
|---|---|---|---|
| 0 | San Diego | - | 16:00 |
| 1 | Ensenada | 08:15 | 16:45 |
| 2 | San Diego | 08:30 | - |
7 - Days
Mexican Riviera
On Disney Wonder
Inside
$1,833
Outside
$2,078
Balcony
$2,442
Suite
$5,095
| Day | Location | Arrive | Depart |
|---|---|---|---|
| 0 | San Diego | - | 16:00 |
| 1 | Fun Day at Sea | - | - |
| 2 | Cabo San Lucas | 08:30 | 16:45 |
| 3 | Mazatlan | 08:30 | 16:45 |
| 4 | Puerto Vallarta | 08:30 | 16:45 |
| 5 | Fun Day at Sea | - | - |
| 6 | Fun Day at Sea | - | - |
| 7 | San Diego | 08:30 | - |
15 - Days
Panama Canal
Inside
$1,879
Outside
$3,049
Balcony
$4,599
Suite
$7,599
| Day | Location | Arrive | Depart |
|---|---|---|---|
| 0 | San Diego - California | - | 17:00 |
| 1 | At Sea | - | - |
| 2 | Cabo San Lucas - Mexico | 12:00 | 18:00 |
| 3 | Puerto Vallarta - Mexico | 12:00 | 19:00 |
| 4 | At Sea | - | - |
| 5 | At Sea | - | - |
| 6 | Puerto Quetzal - Guatemala | 06:30 | 18:00 |
| 7 | At Sea | - | - |
| 8 | Puntarenas - Costa Rica | 08:00 | 18:30 |
| 9 | At Sea | - | - |
| 10 | Panama Canal (Cruising) | 06:00 | 18:00 |
| 11 | Colon - Panama | 06:00 | 16:00 |
| 12 | Cartagena - Colombia | 09:00 | 16:00 |
| 13 | At Sea | - | - |
| 14 | At Sea | - | - |
| 15 | Fort Lauderdale - Florida | 07:00 | - |
5 - Days
Mexican Riviera
On Disney Wonder
Inside
$1,289
Outside
$1,389
Balcony
$1,594
Suite
$2,500
| Day | Location | Arrive | Depart |
|---|---|---|---|
| 0 | San Diego | - | 16:00 |
| 1 | Fun Day at Sea | - | - |
| 2 | Cabo San Lucas | 08:30 | 16:45 |
| 3 | Fun Day at Sea | - | - |
| 4 | Ensenada | 08:30 | 16:45 |
| 5 | San Diego | 08:30 | - |
14 - Days
Panama Canal
On Disney Wonder
Inside
$2,463
Outside
$3,079
Balcony
$5,165
Suite
$8,609
| Day | Location | Arrive | Depart |
|---|---|---|---|
| 0 | San Diego | - | 16:00 |
| 1 | Fun Day at Sea | - | - |
| 2 | Cabo San Lucas | 08:30 | 16:45 |
| 3 | Puerto Vallarta | 10:30 | 16:45 |
| 4 | Fun Day at Sea | - | - |
| 5 | Fun Day at Sea | - | - |
| 6 | Fun Day at Sea | - | - |
| 7 | Fun Day at Sea | - | - |
| 8 | Panama Canal | - | - |
| 9 | Cartagena | 10:00 | 17:45 |
| 10 | Fun Day at Sea | - | - |
| 11 | Grand Cayman | 07:00 | 15:00 |
| 12 | Cozumel | 09:00 | 16:45 |
| 13 | Fun Day at Sea | - | - |
| 14 | Galveston | 08:00 | - |
| Day | Location | Arrive | Depart |
|---|
| Day | Location | Arrive | Depart |
|---|---|---|---|
| 0 | San Diego, California, Us | - | 17:00 |
| 1 | At Sea | - | - |
| 2 | At Sea | - | - |
| 3 | Puerto Vallarta, Mexico | 07:00 | 16:00 |
| 4 | At Sea | - | - |
| 5 | Huatulco, Mexico | 08:00 | 14:00 |
| 6 | Puerto Quetzal, Guatemala | 09:00 | 19:00 |
| 7 | Corinto, Nicaragua | 08:00 | 16:00 |
| 8 | Puerto Caldera (Puntarenas), Costa | 08:00 | 18:00 |
| 9 | At Sea | - | - |
| 10 | Enter Panama Canal Balboa | 05:00 | 05:00 |
| 11 | Cruising Panama Canal | - | - |
| 12 | Exit Panama Canal Cristobal | 19:00 | 19:00 |
| 13 | Cartagena, Colombia | 12:00 | 18:00 |
| 14 | At Sea | - | - |
| 15 | At Sea | - | - |
| 16 | Half Moon Cay, Bahamas | 08:00 | 15:00 |
| 17 | Fort Lauderdale, Florida, Us | 07:00 | - |
| Day | Location | Arrive | Depart |
|---|
| Day | Location | Arrive | Depart |
|---|---|---|---|
| 0 | San Diego, California, Us | - | 17:00 |
| 1 | At Sea | - | - |
| 2 | At Sea | - | - |
| 3 | At Sea | - | - |
| 4 | At Sea | - | - |
| 5 | At Sea | - | - |
| 6 | Kona, Hawaii, Us | 07:00 | 18:00 |
| 7 | Scenic Cruising Kilauea Volcano | - | - |
| 8 | Hilo, Hawaii, Us | 08:00 | 18:00 |
| 9 | Honolulu, Hawaii, Us | 07:00 | - |
| 10 | Honolulu, Hawaii, Us | - | 23:00 |
| 11 | Nawiliwili, Kauai, Hawaii, Us | 08:00 | 18:00 |
| 12 | Lahaina, Hawaii, Us | 07:00 | 23:00 |
| 13 | At Sea | - | - |
| 14 | At Sea | - | - |
| 15 | At Sea | - | - |
| 16 | At Sea | - | - |
| 17 | At Sea | - | - |
| 18 | Ensenada, Mexico | 18:00 | 23:59 |
| 19 | San Diego, California, Us | 07:00 | - |
| Day | Location | Arrive | Depart |
|---|---|---|---|
| 0 | San Diego, California, Us | - | 17:00 |
| 1 | At Sea | - | - |
| 2 | Cabo San Lucas, Mexico | 10:00 | 18:00 |
| 3 | Loreto, Mexico | 10:00 | 23:00 |
| 4 | Pichilingue (La Paz), Mexico | 08:00 | 15:00 |
| 5 | Mazatlan, Mexico | 08:00 | 18:00 |
| 6 | Puerto Vallarta, Mexico | 08:00 | - |
| 7 | Puerto Vallarta, Mexico | - | 17:00 |
| 8 | At Sea | - | - |
| 9 | At Sea | - | - |
| 10 | San Diego, California, Us | 07:00 | - |
| Day | Location | Arrive | Depart |
|---|---|---|---|
| 0 | San Diego, California, Us | - | 17:00 |
| 1 | At Sea | - | - |
| 2 | At Sea | - | - |
| 3 | Puerto Vallarta, Mexico | 07:00 | 16:00 |
| 4 | At Sea | - | - |
| 5 | Huatulco, Mexico | 08:00 | 14:00 |
| 6 | Puerto Quetzal, Guatemala | 09:00 | 19:00 |
| 7 | Corinto, Nicaragua | 08:00 | 16:00 |
| 8 | Puerto Caldera (Puntarenas), Costa | 08:00 | 18:00 |
| 9 | At Sea | - | - |
| 10 | Enter Panama Canal Balboa | 05:00 | 05:00 |
| 11 | Cruising Panama Canal | - | - |
| 12 | Exit Panama Canal Cristobal | 19:00 | 19:00 |
| 13 | Cartagena, Colombia | 12:00 | 18:00 |
| 14 | At Sea | - | - |
| 15 | At Sea | - | - |
| 16 | Key West, Florida, Us | 08:00 | 17:00 |
| 17 | Fort Lauderdale, Florida, Us | 07:00 | - |
San Diego Departures
Ready to embark on an island getaway, or a trip down to Mexico? How about a tour of the west coast and Canada where your every whim is catered to by an expert crew? These cruises from San Diego have it all, and offer the perfect opportunity to enjoy a great California city before your departure.
Search and you’ll find many Mexico cruises from San Diego, with each guaranteeing exceptional service and world-class luxury as they make their way south of the border. Hop aboard the Holland America Line’s MS Oosterdam ship for a 7-night round-trip expedition to the Mexican Riviera, bring the whole family on Disney Cruise Line’s Wonder ship, where you can all enjoy a 2-, 3- or 5-night cruise to Baja — whatever one you choose you’ll be in for an unforgettable vacation.
Cruises to Hawaii from San Diego are also available, with popular 18- and-25 night tours of the islands aboard the MS Oosterdam and as well as Holland’s MS Westerdam. Both ships are like bustling cities on the sea, with some of the best food and entertainment you’ll find anywhere, let alone on a cruise ship. And if you’re based in San Diego and the cruise options leave room to be desired, don’t rule out cruises from other California ports, such as the Port of Long Beach, just outside of Los Angeles. With countless ports connected by travel routes, you can continue to travel to your heart’s content.
Of course, Dunhill Travel Deals makes all of this as simple as a click of the mouse. Just plot your course of action and we’ll take care of the rest. With a number of cruises out of San Diego, it’s important that you find the one that suits you, at the price you deserve, so we cut your search down to only the best and most value-friendly results.
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